ABSTRACT
Respiratory syncytial virus (RSV) infection remains a major public health problem, especially in younger children and the elderly. But several monoclonal antibodies, antivirals and vaccines, either recently launched or in development, offer new hope for RSV prevention and treatment.Copyright © 2023 Wiley Interface Ltd.
ABSTRACT
Ongoing research into the use of messenger RNA (mRNA) vaccines for the treatment of cancer has been expediated by the coronavirus pandemic because similar technology was used in the development of mRNA COVID-19 vaccines. So how close are we now to the widespread clinical use of mRNA anti-cancer vaccines?.Copyright © 2023 Wiley Interface Ltd.
ABSTRACT
The monoamine hypothesis of depression has dominated treatment for decades, but for some with treatment-resistant depression, alternative approaches are needed. This article discusses some of the other mechanisms involved in depression and how novel treatments could address these.Copyright © 2023 Wiley Interface Ltd.
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CRISPR is a gene editing technique that has revolutionised research and has the potential to transform the treatment of many diseases. This article discusses the principles of the technique, its therapeutic applications and potential safety issues.
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Forty years has passed since the first cases of an illness subsequently identified as AIDS were reported, yet despite extensive research and many clinical trials, an HIV vaccine is still not available. However, there is now renewed optimism that a vaccine with broad activity against several HIV variants is possible.
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The rapid increase in applications for bail was one of the earliest responses to COVID-19 across the Victorian court system. As the courts addressed the challenges that the pandemic posed it was accepted that COVID-19 would be taken into account as a surrounding circumstance relevant to the determination of bail applications. The consideration of conditions in custody under COVID-19 restrictions as a factor relevant to the determination of bail applications has highlighted the need for greater communication and transparency of the onerous conditions for prisoners under COVID-19 restrictions. While it was established that the impact of the pandemic on those in custody would be assessed by the courts on a case by case basis, the paucity of information on lockdown conditions within Victorian prisons has impeded the court’s ability to assess the competing considerations before it in determining questions of bail. © 2021 Sydney Institute of Criminology.